Put simply, the stage describes how widespread or advanced the cancer is in the breast tissue and possibly other parts of your body. Determining the stage helps doctors explain the breadth of the cancer to you. Breast cancer is also classified according to other characteristics.
However, the prognosis of patients with this stage is still highly variable. This study was carried out to investigate the validity of metastatic axillary lymph node ratio mALNR as a predictor of long-term prognosis in stage IIIC breast cancer. Medical records of patients who underwent surgery with more than level II axillary dissection for breast cancer and who were diagnosed with pN3 by pathology between andwere reviewed.
Stage 3 means that the cancer has spread from the breast to lymph nodes close to the breast or to the skin of the breast or to the chest wall. Stage 3B means the tumour has spread to the skin of the breast or the chest wall. The cancer has made the skin break down an ulcer or caused swelling.
T followed by a number from 0 to 4 describes the main primary tumor's size and if it has spread to the skin or to the chest wall under the breast. This includes inflammatory breast cancer. N followed by a number from 0 to 3 indicates whether the cancer has spread to lymph nodes near the breast and, if so, how many lymph nodes are involved.
Stage 3 cancer means the breast cancer has extended to beyond the immediate region of the tumor and may have invaded nearby lymph nodes and muscles, but has not spread to distant organs. Although this stage is considered to be advanced, there are a growing number of effective treatment options. The difference is determined by the size of the tumor and whether cancer has spread to the lymph nodes and surrounding tissue.
Stage 3 breast cancer is more advanced than stage 2 but is not considered metastatic. With stage 3, cancer has not spread from the breast to organs or other distant sites in the body. Instead, cancer cells are constrained to nearby axillary underarm lymph nodes or those beneath your sternum breastbone or clavicle collarbone. A stage 3 breast tumor can range in size from less than 2 centimeters to over 5 centimeters, but there are cases in which no tumor is found in breast tissue.
Overview Stage III breast cancer is characterized by one of the following:. Breast cancer that has spread to the lymph nodes is commonly referred to as node-positive disease. Effective treatment of stage III breast cancer requires both local and systemic therapy.