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SPORE in Pancreatic Cancer Focus is on translational studies that address basic and clinical issues of importance to improving outcome of patients with pancreatic cancer. Chi Lin, M. Charles A.

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Transanal endoscopic microsurgery TEM for the treatment of early-stage rectal cancer has attracted attention due to its advantages of reduced surgical trauma, fewer complications, low operative mortality, rapid postoperative recovery and short hospital stay. However, there are still significant controversies regarding TEM for the treatment of rectal cancer, mainly related to the prognosis associated with this method. This study sought to compare the efficacy of transanal endoscopic microsurgery TEM and total mesorectal excision TME for the treatment of T1 rectal cancer.

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MethylSeqDesign: a framework for Methyl-Seq genome-wide power calculation and study design issues. MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis. DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions.

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The pectinate line dentate line is a line which divides the upper two thirds and lower third of the anal canal. Developmentally, this line represents the hindgut - proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:.

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It is particularly useful when there are much more predictors than the sample size. This paper proposes a Bayesian method to solve the elastic net model using a Gibbs sampler. While the marginal posterior mode of the regression coefficients is equivalent to estimates given by the non-Bayesian elastic net, the Bayesian elastic net has two major advantages.

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