Impact factor 3. International Journal of Biological Sciences. International Journal of Medical Sciences.
Chemotherapy for breast cancer uses drugs to target and destroy breast cancer cells. These drugs are usually given directly into a vein through a needle or as a pill. Chemotherapy for breast cancer frequently is used in addition to other treatments, such as surgery, radiation or hormone therapy.
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Although breast cancer is not easily controlled, the spread of breast cancer is sometimes predictable. The cancer cells spread through a customary path, out from the tumor and into the surrounding lymph nodes, before they progress throughout the body. A sentinel lymph node biopsy is a procedure to examine the lymph node closest to the tumor because this is where the cancer cells have most likely spread. To be able to identify the sentinel lymph node, the surgeon will inject dye or radioactive substances into the tissue near the tumor.
Cells in the body normally divide reproduce only when new cells are needed. Sometimes, cells in a part of the body grow and divide out of control, which creates a mass of tissue called a tumor. If the cells that are growing out of control are normal cells, the tumor is called benign not cancerous.
The presence of cancer cells is known as lymph node involvement. Lymph nodes are small, bean-shaped organs that act as filters along the lymph fluid channels. As lymph fluid leaves the breast and eventually goes back into the bloodstream, the lymph nodes try to catch and trap cancer cells before they reach other parts of the body.
Put simply, the stage describes how widespread or advanced the cancer is in the breast tissue and possibly other parts of your body. Determining the stage helps doctors explain the breadth of the cancer to you. Breast cancer is also classified according to other characteristics. Learn more about how specialists at MSK classify types of breast cancer.
Lymph nodes are small clumps of immune cells that act as filters for the lymphatic system. The lymphatic system runs throughout the body like the circulatory blood system and carries fluid and cells. Figure 4.
October 10,by NCI Staff. New study results show that for women with early-stage breast cancer, having only a sentinel lymph node biopsy after lumpectomy, rather than a more aggressive biopsy procedure, did not decrease survival. Long-term results from a large clinical trial confirm that, for some women with early-stage breast cancer who have lumpectomy as their surgical treatment, a less extensive lymph node biopsy approach is sufficient. The trial showed that women with early-stage breast cancer who have cancer cells in one or two sentinel lymph nodes can skip axillary lymph node dissection ALND after breast-conserving surgery without affecting their long-term survival.